Coronavirus symptoms update: Neurological and psychiatric issues found in even mild cases

Across the whole dataset, the most common neurological and psychiatric symptoms were anosmia (loss of smell; reported by 43 percent of patients with COVID-19), weakness (40 percent), fatigue (38 percent), dysgeusia (loss of taste; 37 percent), myalgia (muscle pain; 25 percent), depression (23 percent), headache (21 percent) and anxiety (16 percent). They also identified the presence of major neurological disorders such as ischaemic stroke (1.9 percent of cases in the dataset), haemorrhagic stroke (0.4 percent) and seizure (0.06 percent).

Patients with severe COVID-19 were overrepresented in the dataset as a whole, as most of the studies focused on hospitalised patients, and even the studies of people outside of hospital included few people with very mild or no symptoms.

However, among people with symptomatic acute COVID-19 who were not hospitalised, neurological and psychiatric symptoms were still common: 55 percent reported fatigue, 52 percent loss of smell, 47 percent muscle pain, 45 percent loss of taste, and 44 percent reported headaches.

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